| Product Information | |
|---|---|
| CAS number | 71-36-3 |
| EC index number | 603-004-00-6 |
| EC number | 200-751-6 |
| Grade | NF |
| Hill Formula | C₄H₁₀O |
| Chemical formula | CH₃(CH₂)₃OH |
| Molar Mass | 74.12 g/mol |
| HS Code | 2905 13 00 |
| Structure formula Image |  |
| Applications | |
|---|---|
| Application | 1-Butanol suitable for use as excipient EMPROVE® exp NF. CAS 71-36-3, chemical formula CH₃(CH₂)₃OH. |
| Physicochemical Information | |
|---|---|
| Boiling point | 116 - 118 °C (1013 hPa) |
| Density | 0.81 g/cm3 (20 °C) |
| Explosion limit | 1.4 - 11.3 %(V) |
| Flash point | 34 °C |
| Ignition temperature | 340 °C |
| Melting Point | -89 °C |
| pH value | 7 (70 g/l, H₂O, 20 °C) |
| Vapor pressure | 6.7 hPa (20 °C) |
| Solubility | 66 g/l |
| Toxicological Information | |
|---|---|
| LD 50 oral | LD50 Rat 790 mg/kg |
| LD 50 dermal | LD50 Rabbit 3400 mg/kg |
| Safety Information according to GHS | |
|---|---|
| Hazard Pictogram(s) | |
| Hazard Statement(s) | H226: Flammable liquid and vapour. H302: Harmful if swallowed. H315: Causes skin irritation. H318: Causes serious eye damage. H335: May cause respiratory irritation. H336: May cause drowsiness or dizziness. |
| Precautionary Statement(s) | P210: Keep away from heat. P280: Wear eye protection. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P313: Get medical advice/ attention. |
| RTECS | EO1400000 |
| Storage class | 3 Flammable liquids |
| WGK | WGK 1 slightly water endangering |
| Disposal | 1 Strongly contaminated halogen-free organic solvents: container A. |
| Safety Information | |
|---|---|
| Hazard Symbols | Harmful |
| Categories of danger | flammable, harmful, irritant |
| R Phrase | R 10-22-37/38-41-67 Flammable.Harmful if swallowed.Irritating to respiratory system and skin.Risk of serious damage to eyes.Vapours may cause drowsiness and dizziness. |
| S Phrase | S 7/9-13-26-37/39-46 Keep container tightly closed and in a well-ventilated place.Keep away from food, drink and animal feedingstuffs.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable gloves and eye/face protection.If swallowed, seek medical advice immediately and show this container or label. |
| Storage and Shipping Information | |
|---|---|
| Storage | Store at +5°C to +30°C. |
| Transport Information | |
|---|---|
| Declaration (railroad and road) ADR, RID | UN 1120 , 3, III |
| Declaration (transport by air) IATA-DGR | UN 1120 , 3, III |
| Declaration (transport by sea) IMDG-Code | UN 1120 , 3, III |
| Specifications | |
|---|---|
| Purity (GC) | ≥ 99.5 % |
| Identity (IR) | conforms |
| Identity (B) | conforms |
| Acidity | conforms |
| Limit of Butyraldehyde, 2-Butanol, Isobutyl alcohol and Butyl ether (GC) | conforms |
| Butyraldehyde (GC) | ≤ 0.1 % (v/v) |
| 2-Butanol (GC) | ≤ 0.1 % (v/v) |
| 2-Methylpropan-1-ol (GC) | ≤ 0.1 % (v/v) |
| Butyl ether (GC) | ≤ 0.2 % (v/v) |
| Residual solvents class 3 (ICH Q3C) | < 0,5 % |
| Other residual solvents (ICH Q3C) | excluded by production process |
| Evaporation residue | ≤ 0.0040 % |
| Water | ≤ 0.10 % |
| Residue of metal catalysts or metal reagents according to EMEA/CHMP/SWP/4446/2000 are not likely present. Conforms to NF |
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