بوتیل هیدروکسی تولوئن 817074 مرک

Product Information
CAS number	128-37-0
EC number	204-881-4
Grade	Ph Eur,JPE,NF,E 321
Hill Formula	C₁₅H₂₄O
Molar Mass	220.35 g/mol
HS Code	2907 19 90
Structure formula Image

Applications
Application	Butylhydroxytoluene Ph Eur,JPE,NF,E 321. CAS 128-37-0, molar mass 220.35 g/mol.

Physicochemical Information
Boiling point	265 °C (1013 hPa)
Density	1.05 g/cm3 (20 °C)
Flash point	127 °C
Ignition temperature	345 °C
Melting Point	69 - 70 °C
Vapor pressure	0.02 hPa (20 °C)
Bulk density	450 kg/m3
Solubility	<0.001 g/l

Toxicological Information
LD 50 oral	LD50 Rat > 2000 mg/kg

Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s)	H410: Very toxic to aquatic life with long lasting effects.
Precautionary Statement(s)	P273: Avoid release to the environment.
RTECS	GO7875000
Storage class	10 - 13 Other liquids and solids
WGK	WGK 2 water endangering

Safety Information
Hazard Symbols	Dangerous for the environment
Categories of danger	dangerous for the environment
R Phrase	R 50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
S Phrase	S 61 Avoid release to the environment. Refer to special instructions/ Safety data sheets.

Storage and Shipping Information
Storage	Store at +15°C to +25°C.

Transport Information
Declaration (railroad and road) ADR, RID	UN 3077 , 9, III
Declaration (transport by air) IATA-DGR	UN 3077 , 9, III
Declaration (transport by sea) IMDG-Code	UN 3077 , 9, III, Marine Pollutant: P

Specifications
Assay (GC)	≥ 99.0 %
Assay (HPLC)	99.0 - 101.5 %
Identity (Identification 1 (JPE))	passes test
Identity (IR-spectrum)	passes test
Identity (Identification 2 (JPE))	passes test
Identity (HPLC)	passes test
Appearance	White to yellowish crystalline powder.
Appearance of solution (100 g/l, methanol (Ph. Eur.))	Clear and not more intense in color than reference solutionY₅ or BY₅ (Ph. Eur.).
Appearance of solution (100 g/l, ethanol (95 )% (JPE))	Clear and colorless.
Solidification temperature	69.2 - 70.0 °C
Melting point	69.5 - 72.0 °C
Absorption maximum λmax. (ethanol abs.)	277 - 279 nm
Spec. Absorptivity A 1%/1cm (λmax; 0.02 g/l; ethanol abs.)	81 - 88
Spec. Absorptivity A 1%/1cm (λ₂₇₈ nm; 0.05 g/l; ethanol (95 %))	82 - 88
Heavy metals (as Pb)	≤ 10 ppm
Sulphate (SO₄)	≤ 150 ppm
As (Arsenic)	≤ 3 ppm
Hg (Mercury)	≤ 1 ppm
Pb (Lead)	≤ 2 ppm
tert-butanol (GC)	≤ 1000 ppm
Diisobutylene (GC)	≤ 100 ppm
p-Cresol	≤ 0.1 %
2-Propanol (GC)	≤ 2000 ppm
Related substances (TLC)	≤ 0.5 %
Related substances (HPLC) (p-Cresol oder m-cresol)	≤ 0.1 %
Related substances (HPLC) (3-tert-Butyl-4-hydroxyanisole)	≤ 0.1 %
Related substances (HPLC) (3,5-Di-tert-butyl-4-hydroxybenzoic acid)	≤ 0.1 %
Related substances (HPLC) (2-tert-Butyl-4-methylphenol or 2-tert-butyl-5-methylphenol)	≤ 0.1 %
Related substances (HPLC) (3,5-Di-tert-butyl-4-hydroxy benzaldehyde)	≤ 0.1 %
Related substances (HPLC) (4,6-Di-tert-butyl-m-cresol)	≤ 0.1 %
Related substances (HPLC) (2,6-Di-tert-butyl-phenol)	≤ 0.1 %
Related substances (HPLC) (Any unspecified impurity)	≤ 0.1 %
Related substances (HPLC) (Sum of all impurities)	≤ 0.7 %
Other residual solvents (ICH Q3C)	passes test
Sulfated ash (600 °C)	≤ 0.002 %
Water (according to Karl Fischer)	≤ 0.2 %
Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present.
Corresponds to Ph. Eur., JPE, NF, E 321. Conforms to the purity criteria on food additives according to the current European Commission Regulation.