سدیم استات تری هیدرات 106235 مرک Sodium acetate trihydrate 106235 merck
سدیم استات تری هیدرات 106235 مرک
Sodium acetate trihydrate 106235 merck
Sodium acetate trihydrate suitable for use as an active pharmaceutical ingredient EMPROVE(r) api Ph Eur,BP,JP,USP,FCC,E 262.
Product Information
CAS number 6131-90-4
EC number 204-823-8
Grade Ph Eur,BP,JP,USP,FCC,E 262
Hill Formula C₂H₃NaO₂ * 3 H₂O
Chemical formula CH₃COONa * 3 H₂O
Molar Mass 136.08g/mol
HS Code 2915 29 00
Structure formula Image
Applications
Application Sodium acetate trihydrate suitable for use as an active pharmaceutical ingredient EMPROVE(r) api Ph Eur,BP,JP,USP,FCC,E 262. CAS No. 6131-90-4, EC Number 204-823-8.
Physicochemical Information
Density 1.42g/cm3 (20C)
Flash point >250C(anhydrous substance)
Ignition temperature 607C
Melting Point 58C
pH value 7.5-9.2 (50g/l, H₂O, 20C)
Bulk density 900kg/m3
Solubility 613g/l
Toxicological Information
LD 50 oral LD50 Rat 3530 mg/kg
LD 50 dermal LD50 Rabbit > 10000 mg/kg
Safety Information according to GHS
RTECS AJ4580000
Storage class 10 - 13 Other liquids and solids
WGK WGK 1 slightly water endangering
Disposal 14
Inorganic salts: Container I. Neutral solutions of the these salts: Container D. Before placing in Container D, check the pH with pH-Universal indicator strips (Item No. 109535).
Storage and Shipping Information
Storage Store at +2C to +25C.
Transport Information
Declaration (railroad and road) ADR, RID Kein Gefahrgut
Declaration (transport by air) IATA-DGR No Dangerous Good
Declaration (transport by sea) IMDG-Code No Dangerous Good
Specifications
Assay (perchloric acid titration, calculated on dried substance) 99.5 - 101.0%
Identity passes test
Appearance of solution passes test
In water insoluble matter 0.03%
Alkalinity 0.05%
Acidity or alkalinity passes test
pH-value (1 %, water) 8.0 - 9.5
pH-value (5 %; water) 7.5 - 9.0
Chloride (Cl) 0.005%
Sulphate (SO₄) 0.003%
Heavy metals (as Pb) 0.0006%
Al (Aluminium) 0.00002%
As (Arsenic) 0.0002%
Ca (Calcium) 0.002%
Fe (Iron) (*) 0.001%
Hg (Mercury) 0.0001%
K (Potassium) 0.005%
Mg (Magnesium) 0.001%
Pb (Lead) 0.0002%
Ca + Mg (calcium and magnesium) passes test
free acetic acid 0.4%
Other residual solvents (Ph.Eur./USP/ICH) excluded by manufacturing process
formic acid, formate and other oxidizable impurities 0.1%
Substances reducing potassium permanganate (as HCOOH) passes test
Loss on drying (130 C) 39.0 - 40.5%
* specified acc. to EMEA/CHMP/SWP/4446/2000.Other residues of metal catalysts or metal reagents acc. to this guideline are not likely to be present.
Corresponds to Ph Eur,BP,JP,USP,FCC,E 262
Conforms to the purity criteria on food additives according to the current European Commission Regulation.